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10.1016/j.msec.2011.04.010 26 DheerD.AroraD.JaglanS.RawalR
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hope this answer is helpful B6 overdose resulting in neurological symptoms would require daily B6 doses of 100mg for months to years (or B6 injections)
One of the most promising interventions is dietary restriction (DR) of either calories in general or specific macronutrients, as it consistently has been shown to prolong life- and healthspan in a broad range of model organisms and possibly humans, too, when compared with unrestricted food intake
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