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The comparability of patient characteristics between two study groups was achieved by the three-step matching on (1) the index date, (2) prior exposure to GLAs in the year before the index date, and (3) patient demographic and clinical characteristics (e.g., diabetes severity, comorbidities, co-medications for cardiovascular diseases [CVDs]) using the propensity score matching approach [6]
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This comprehensive approach optimizes sustained weight loss while mitigating side effects, preserving muscle mass, and limiting nutritional deficiencies." A study by Italian scientists concluded that people risk regaining their lost weight when they rely solely on GLP-1 therapies
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