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"Furthermore, despite clomiphene citrate's association with significant increases in sperm concentration, it is not universally effective, with a meta-analysis indicating a significant increase in sperm concentration in approximately 60% of men." For men who have obesity and oligospermia but normal levels of testosterone and estradiol, "conventional pharmaceutical approaches like clomiphene may not be suitable," the authors wrote

These research studies have been proven by testing on humans and animals with assisted reproductive technology

Eur Urol (2015) 68(4):67480

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