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The NIH Office of Dietary Supplements, citing Institute of Medicine recommendations, advises that it is advisable for those older than 50 years to meet their RDA mainly by consuming foods fortified with vitamin B12 or a supplement containing vitamin B12. This recommendation reflects the fact that 10 to 30% of older adults lose the ability to efficiently absorb naturally occurring B12 from food

It acts as an critical antioxidant in many organisms such as plants, fungi, protozoa, bacteria, and humans

GPX8 can inhibit the oxidative stress response of hepatocellular carcinoma cells ( A great deal of research on the structure and function of GPX in mammals has helped us understand the essential functions of this class of proteins