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As some gut bacteria rely on the shikimate pathway for nutrient synthesis or metabolic cross-feeding, glyphosate exposure may alter microbial composition, as 1226% of human gut bacterial species may be sensitive to glyphosate (Leino et al., 2021

[1] Dose-escalation studies, such as a 12-week trial on gradual titration, revealed that beginning at lower doses (e.g., 4 mg) and slowly increasing to therapeutic levels significantly reduced the incidence of nausea, vomiting, and diarrhoea

For many patients, thats meaningful particularly early in treatment when theyre still determining whether GLP-1 therapy will work for them

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