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We chose the 15 wk HFD + L-NAME model and, to gain perspective on potential limitation or reversal of disease phenotype by NO 2 -OA, we treated mice with NO 2 -OA (HFD + L-NAME NO 2 -OA), non-electrophilic oleic acid (HFD + L-NAME OA) or vehicle (HFD + L-NAME vehicle) during wk 12 to 15 via osmotic pumps (Figs

One is by up-regulating a signaling protein called VEGF (vascular endothelial growth factor), which encourages the growth of new capillaries

You may have heard the term GLP-1, but what does it mean

Image Credit: VectorMine / Shutterstock In a recent review published in the British Journal of Pharmacology , the authors reviewed how glucagon-like peptide 1 receptor (GLP-1) agonists may reduce alcohol and drug-seeking behaviors and evaluated their potential as treatments for addictive disorders