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is supported by the Howard Hughes Medical Institute Investigator Program and NIH (R35CA220449, P50CA196516)
Rapid or significant weight loss can suppress reproductive function by reducing leptin and oestrogen levels, disrupting gonadotrophin-releasing hormone secretion
10.4093/dmj.2023.0277 7 CanforaE
The estimated mean annualized bleeding rate (ABR) (primary endpoint) was significantly lower with fitusiran compared to on-demand treatment (3.1 versus 31, respectively
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