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At 52 weeks, tirzepatide led to a reduction of 25.3 events/hour, compared to a reduction of 5.3 events/hour with the placebo, for a treatment difference of 20.0 events/hour
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This issue was further evidenced by improvements in nutritional status, decreases in the levels of inflammatory markers, and slower decreases in residual kidney function when an ultrapure dialysis system was used instead [34, 35]
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