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Nature Rev Endocrinol
Covert hepatic encephalopathy consists of minimal and grade 1 hepatic encephalopathy 1 , could impair the cognitive function, lower work efficiency, reduce the quality of life 6,7 , impair driving skills 8,9,10,11 , or results in poor prognosis 12,13,14
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All animal experiments were approved by The Medical Ethics Committee of Tongji Medical College (IACUC: 3688), Huazhong University of Science and Technology, and performed according to the National Institutes of Health animal use guidelines on the use of experimental animals
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