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Understanding how the microbiome is involved in establishing, maintaining, and reversing obesity has been an active area of research 14,15,16 , and has included studies investigating links between the microbiome and obesity-related comorbidities such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) 17,18
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Hormone Res Paediatrics 55:278281
Preclinical research includes laboratory, cell, tissue, and animal studies conducted before adequate controlled human clinical validation
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