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Sikiric et al., 1993
Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood
However, some stem cell populations share surface markers and signaling features with senescent cells, raising a theoretical concern about off-target effects on tissue-resident stem cells
GAPDH is included as loading control
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