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Growth/differentiation factor-15 (GDF-15) is a placental protein, which is barely detected in most somatic tissues in humans

[118] Methionine synthase [edit] Methionine synthase, coded by MTR gene, is a methyltransferase enzyme which uses the MeB 12 and reaction type 2 to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine

Pre-fractionation increased peptide coverage and improved NAPQI-peptide discovery due to better resolution of peptides, thus reducing matrix effects in both MRM and DDA