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Estimation of biochemical parameters The Table 3 shows the increased level of Cholesterol, TG and LDL in the HCD rats as compared with the NC, whereas HDL was significantly reduced

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The mouse MASH model was established using a high-fat diet combined with carbon tetrachloride (CCl 4 ) induction, and efficacy tests were conducted with both semaglutide and tirzepatide (Fig.4)

Autopsy studies of elderly patients with IPF have highlighted the severity and irreversibility of fibrotic remodeling in aged tissues, underscoring the importance of targeted therapeutic interventions [6]