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Stress, poor nutrition, environmental toxins, and ongoing oxidative stress can all contribute to lower levels
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Neither glutathione trisulfide (GSSSG, a potent anti-oxidant) nor lipoic acid enhanced c-met binding or nitration resistance, and thus served as controls
In the second case, even though the rats are fasted, the rapid reuptake of cysteine, glycine, and glutamate by the liver cells insures that the synthesis of GSH declines relatively slowly and therefore the observed half-life is long
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