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The effect of GLP-1R agonists liraglutide and exendin-4 was examined in vivo on CD-1, MCF-1, MDA-MB-468, MDA-MB-231, 4T1, LNCap, PANC-1, MIA PaCa-2, CT26, SKOV-3, and Apc(Min/+) cell lines expressed in cancers such as thyroid, breast, prostate, pancreatic, colon, ovarian, intestinal, and liver (Table 2)
This activation reduces oxidative stress and inflammation, while also restoring gut barrier integrity and stabilizing the gut microbiota
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