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It is usually considered for patients who have reached their goals and prefer to trial life off medication, those with ongoing intolerance, new contraindications, pregnancy plans, access or cost barriers, or a change in clinical priorities

Vitamin C is also associated with hydroxylation of tyrosine in the synthesis of catecholamines (dopamine, noradrenaline, and adrenaline) and homogentisic acid, the precursor of tocopherols and plastoquinones (Table 1)

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