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Bisphenol-A treatment induces the expression of the regulator GSK-3 (glycogen synthase kinase 3 ) in the hippocampus and SVZ, consequently reducing the ratio of phospho-GSK-3/GSK-3 and enhancing the phospho--catenin/-catenin one
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Exosomes derived from mesenchymal stem cells(MSC-EXO) were found to regulate the AKT/ERK signaling pathway by delivering bioactive proteins, thereby inhibiting NRF2-mediated ferroptosis and improving the function and quantity of cells, which may serve as a novel drug carrier for islet-targeted therapy [90]
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