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By 3 months, those on exenatide had a mean reduction of 7.7 monthly headache days (from a baseline of ~ 22 days/month) compared to a 1.5 day change in the placebo arm, although the between-group difference did not reach statistical significance (exenatide: p = 0.069 within-group
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However, these responses are highly variable, and many people will find they are able to consume coffee as they desire. This response might be related to how Wegovy impacts digestion and appetite
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