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Early in treatment, nausea and reduced appetite often cause rapid weight loss
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Pharmacological autophagy activators: mTOR inhibitors and AMPK/SIRT1 activators Autophagy activators that target nutrient-sensing pathways, such as the mTOR and AMPK/SIRT1 pathways, have attracted interest because of their mechanistic links to aging, metabolism, and cellular homeostasis
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