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In the 1990s, SGLT2i precursors were isolated from phlorizin, a compound found primarily in the root bark of apple trees known to cause glycosuria since 1886 (98) (Figure 3)
Frontiers in Pharmacology , 13, p.964321
Gabaglio M, Zamberletti E, Maneti C, Parolaro D, Rubino T
Recently, GLP-1 was highlighted as a regulator of diverse pathways, but its potential as the therapeutic target of depressive disorder was not described comprehensively
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