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Key safety measures include: Dose optimization: Initiating therapy at the lowest effective doses Blood-pressure monitoring: Regular assessment due to additive vascular effects Prescribed administration: Strict adherence to clinician-directed timing and dosing Potential Side Effects of Combination Therapy Combination therapy may result in additive side effects from both medications, including nausea, flushing, headache, gastrointestinal discomfort, and blood-pressure changes

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The Epi & Coagulation group had a significantly longer operation time than the coagulation group, but this did not affect the decline in AMH and hemoglobin levels