Erythrocyte studies have previously reported eryptosis inducing concentrations for oridonin, cordycepin and apigenin on nave erythrocytes at 25 M, 31 M, and 15 M, respectively ( Among the six eryptosis inducer compounds tested in our study, only apigenin and amiodarone have been previously tested on malaria parasites ( P
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Foods that boost glutathione or its precursors include: Sulfur-rich vegetables: broccoli, cauliflower, garlic, onions Protein sources: lentils, eggs, fish, poultry Avocados, spinach, okra Selenium-rich foods: Brazil nuts, sunflower seeds Supplements come in reduced glutathione or liposomal forms (the latter may have better absorption)
As regards the pathogenic mechanisms, the occurrence of an oxidant stress (resulting from an impaired homocysteine metabolism, which modifies the redox status of extra- and intracellular thiols and thus alters the intracellular redox potential) might play a central role in moderate hyperhomocysteinemia-mediated vascular disorders