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Moreover, CXCL12 and CCL5 play an important role in immune cell recruitment in affected skin, and serum CXCL12 levels are associated with disease activity.23 Additionally, oxidative stress induces the secretion of chemokines like CXCL16.24 Other cytokines elevated in vitiligo include IL-1, IL-2, IL-17, IL-22, IL-23, and IL-33

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For this reason, our focus remains on options that work within the bodys natural regulatory systems

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