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Melanosis coli has also been described uncommonly with other conditions including inflammatory bowel disease and diverticulosis and with medications including bisacodyl, topical anthralin, and bamboo leaf oil

MT2 also has a broader range of effects due to its action on multiple receptors, which makes a conservative, low-and-slow dosing approach even more important

Your healthcare provider may determine that switching medications is appropriate if your current treatment isn't producing meaningful results

Overall, the model estimated that weight regain would stabilize at about 75 % of the total weight lost during treatment