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Electrochemical experiments [5,6,7,8] demonstrate that in organic solutions, the modification and conversion of vitamin B12 cofactors, including cyanocobalamin and aquacobalamin (hydroxocobalamin), into active forms are complex, with rate constants that exhibit significant energy barriers

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Cuadrado et al., 2020

For bone biology studies, glucocorticoid receptor antagonist controls distinguish GH-specific from residual cortisol-mediated skeletal effects