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Tirzepatide enhances insulin secretion in a glucose-dependent manner, suppresses glucagon when glucose levels are elevated, and delays gastric emptying
To minimize these effects, tirzepatide is initiated at a low dose (2.5 mg once weekly) and gradually increased every 4 weeks
A Practical Guide to Using Medicines to Manage Overweight and Obesity: Weight-Related Comorbidities. NICE, 2024, Accessed 19 Aug
Spacing meals 4-6 hours apart gives semaglutide time to signal fullness and allows your stomach to empty completely before the next meal
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