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Gene expression is calculated with the delta-delta Ct method (2 -Ct ) where the value of mRNA in the control, non-treated group is considered to be equal to 1
Determining the right dosage and frequency is crucial for achieving the best results
It can pass easily to the brain and is both water and fat-soluble Liu and colleagues tested aged rats with oral acetyl-L-carnitine and lipoic acid to see if the supplementation reduced mitochondrial aging in the brain [1] A group from Oregon State University reviewed the literature and suggested that together, acetyl-L-carnitine and lipoic acid were able to protect the heart from aging as well as reverse age-related changes [2]
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