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They affect appetite and the brains reward system, reducing cravings and the perceived reward from drinking

Eli Lilly stated "Lilly is deeply concerned that products fraudulently claimed by compounding pharmacies or counterfeiters to be FDA-approved tirzepatide, Mounjaro, or Zepbound may expose patients to serious health risks." Novo Nordisk said its lawsuits "aim to protect US patients and consumers from deceptive marketing by these entities as well as potentially harmful and improperly compounded drugs claiming to contain semaglutide." At least seven deaths linked to compounded versions of semaglutide, the active ingredient in these medications, have been reported to the FDA

In conclusion, the study found that semaglutide, in combination with lifestyle intervention, was associated with a sustained and clinically relevant reduction in body weight in individuals with overweight or obesity