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In general, UGTs mediate the addition of UDP-hexose to nucleophilic atom (, , or atom) in the acceptor molecule (Mackenzie et al., 2008)
Its function as an antioxidant leads it to be defined as a " Master antioxidant": it is essential not only as a powerful weapon of attack against excess free radicals, but it is also capable of regenerating other antioxidant substances, such as Vitamin C and Vitamin E, which once involved in the neutralization of radicals themselves become unstable radical molecules
Its unique position as a naturally occurring, endogenous gene modulator distinguishes it from synthetic peptides in an important way: it works with the bodys existing regulatory systems rather than overriding them
Modern therapeutic options include intratendinous injections of substances believed to inhibit neovascularization, such as corticosteroids (which can cause collagen sclerosis and long-term damage to the tendon), or of substances that relieve pain by other pathways (acupuncture, extracorporeal shock wave therapy [ESWT]) or that stimulate tendon repair (platelet-rich plasma [PRP]) [12,13,14,15]
