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It is produced naturally by the body and is found in every cell, where it acts as a powerful antioxidant and detoxifier
For de novo NADPH synthesis pathway, correlation studies have revealed that thionicotinamide adenine dinucleotide (NADS) and thionicotinamide adenine dinucleotide phosphate (NADPS), converted from the pro-drug thionicotinamide (TN), act as inhibitors of NADKs through targeting the NAD-binding site of NADKs and decreasing the levels of NADPH
Chronic illness, inadequate nutrition, alcohol use, smoking, and prolonged stress may also reduce levels
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