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The delivery methods also differ considerably - while injections provide controlled, consistent release of medication through subcutaneous administration, patches rely on unproven transdermal delivery that cannot effectively transport the hormone through the skin barrier

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When fluid intake is insufficient or fluid losses are excessive (through sweating, vomiting, or diarrhoea), the kidneys conserve water by producing more concentrated urine

An experimental drug called petrelintide that offers clinically meaningful weight loss with relatively few stomach issues is making its way through the research pipeline