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In recent years, there have been many pre-clinical and clinical studies of sigma receptor (1 and 2) ligands for treating neurological disease
Chen D, Tavana O, Chu B, Erber L, Chen Y, Baer R, et al
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It has previously been suggested that the GT II assay is able to reliably detect mixed infections if the minor genotype/subtype represents at least 2030% of the circulating variants (similarly to Sanger sequencing) 13,35
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