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In general, animals are well-adapted to mobilize metabolic responses and body constituents to survive periods of food scarcity 100
Glucagon-like Peptide-1 Receptor: Mechanisms and Advances in Therapy. Signal Transduction and Targeted Therapy, vol
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Patients with certain FTO and MC4R variants, for example, often show enhanced appetite suppression and weight loss when using dual GLP-1/GIP receptor agonists like tirzepatide, potentially allowing metformin reduction or discontinuation more rapidly
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