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"These results are new and shed light on the reasons for high rates of early discontinuation of semaglutide for weight loss in a real-world setting," said Professor Thomsen

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Although the dosage of addition of sodium butyrate supplementation varied, it was consistently effective in reducing body weight (123, 124), whether it was supplied in drinking water or administered by gavage (125, 126)

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The filtered suspension was centrifuged at 300 g, after which the supernatant was discarded

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