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When this condition presents, it can sometimes be seen with a huge excess of plasma proteins, and this WILL give 'thick blood' [horrible term.] Waldenstrom's Macroglobulinaemia is the classic presentation of extermely high plasma protein [with a Macroglobulin]

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Some portion of intranasally administered peptides may reach the brain through the olfactory pathway, bypassing the blood-brain barrier that limits systemic delivery to CNS tissues