Pay in 4 interest-free payments of $6.41 Learn more
Ships within 48 hours · Estimated delivery Aug 13 - Aug 18
Tips for Budgeting Your Skinny Shot Program Here are a few ways to make your investment go further: Shop packages: Multi-shot plans often lower your cost per injection
Populations of patients using these devices are potentially younger, wealthier, and more active, already engaging with fitness apps to proactively lose weight and manage their health 20,21
5-Amino-1MQ Key Research Facts Chemical name: 5-Amino-1-Methylquinolinium (also abbreviated as 5A-1MQ or 5MQ) Target enzyme: Nicotinamide N-Methyltransferase (NNMT) Mechanism: Competitive inhibition of NNMT reduces 1-MNA production, preserves nicotinamide for NAD+ synthesis and SAM for epigenetic methylation Selectivity: High selectivity for NNMT does not inhibit related SAM-dependent methyltransferases or NAD+ salvage pathway enzymes Membrane permeability: High passive and active transport permeability confirmed in PAMPA and Caco-2 cell assays NNMT expression: Upregulated in obese adipose tissue, multiple cancer types, and aged skeletal muscle tissue contexts of primary research interest Downstream targets: NAD+ availability, SIRT1/SIRT3 activity, SAM-dependent epigenetic methylation, lipogenesis, energy expenditure Pre-clinical models: Diet-induced obese (DIO) mice, 3T3-L1 adipocyte cell models, aged mouse skeletal muscle models, HeLa cancer cell lines In vitro cell viability: No impact on cell viability at 10 M concentration in 3T3-L1 pre-adipocytes in published toxicity profiling What Does 5-Amino-1MQ Do in Research
Industry research standard is 99%+
US$ 27.40
US$ 23.85
US$ 27.61
US$ 20.53
US$ 29.45
US$ 29.40
US$ 29.84
