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Chronically high glucose fuels a flood of free radicals, and over time patients are left with less of the reduced, protective form of GSH and more of the oxidized, exhausted kind a red flag of cellular stress

There is also a mechanism for generalised input from the wider public: each month interviewers seek feedback on the questions from all respondents, who are representative of the population in Great Britain

For the patient, the drug regimen has failed to deliver, and they have wasted their time, money and perhaps experienced severe side effects