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Vitamin B6 has been shown to help reduce nausea, improving comfort and adherence to the treatment plan
The most important factor is consistency of timing and route day to day, since the mechanism works cumulatively rather than as an acute event to time around a meal
1 2 Critical Reviews in Food Science and Nutrition
Elderly patients may be more sensitive to the medications effects and may require slower titration or lower maintenance doses, particularly if they have reduced renal function or are at higher risk for dehydration from gastrointestinal adverse effects
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