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Immunohistochemistry IL6 and TNF analysis showed similar patterns where treatments reduced proinflammatory cytokine expression, with best results in RTDLCI and RTDALCI groups showing the lowest levels
One study of post-menopausal women with PCOS using 4g/day of myo-inositol also found a reduction in fasting glucose, fasting insulin and HOMA-IR ( Inositol supplements in postmenopausal women with metabolic syndrome 2012 )
Moreover, a systematic review and meta-analysis of observational studies demonstrated that blood levels of copper in patients with depression were higher than those of patients without depression, while there was no difference in copper content in the hair between the two groups, suggesting that copper levels in the blood may be more sensitive to pathological changes in patients compared to those in the hair (Harvey et al., 2009
Since the liver plays a role in processing copper and the kidneys in filtering waste, any pre-existing impairment in these organs warrants caution
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