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Upd: As of March 7, 2026, Reuters reported that Novo and Hims had resolved the dispute and planned to sell obesity drugs together

They are more commonly associated with iron deficiency anemia but have also been linked to vitamin C deficiency ( Red spots or vertical lines in the nail bed, known as splinter hemorrhage, may also appear during vitamin C deficiency due to weakened blood vessels that rupture easily

Risks were lower with the GLP-1 receptor agonist for major adverse cardiac events (HR 0.66, 95% CI 0.480.91), venous thromboembolism (HR 0.49), kidney disease progression (HR 0.77) and all-cause mortality (HR 0.26)

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