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Iron supplementation was found to exacerbate disease activity and oxidative stress in a rat model of colitis induced by DSS (10)

PMID: 13 LopezGSalasCACadizFBarrigaCGonzalezPAcevedoSet al

The association between smoking and MASLD is underpinned by shared pathological mechanisms, particularly insulin resistance and visceral fat accumulation, which are central to the metabolic syndrome (MetS)

Moreover, the consistent use of phytochemicals such as polyphenols, flavonoids, and eugenol present in neem and clove may regulate cytokine profiles, modulate microbial flora and sustain epithelial integrity, thus optimizing the tissue environment in which the activity of vitamin D dependent pathways involved in immunoregulation and bone homeostasis can operate to its full potential ( 240 )