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Retatrutide is showing extraordinary promise in clinical trials for severe obesity, but it is still an investigational medication undergoing Phase 3 evaluation because long-term safety, optimal dosing, side effects, and real-world outcomes still need rigorous study before FDA approval

Safety endpoints were treatment-emergent adverse events (TEAEs), serious adverse events (SAEs), and discontinuation due to adverse events (AEs)

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Even in the absence of a previous heart attack or stroke, adults with type 2 diabetes face an increased risk of cardiovascular events, underscoring the need for therapies that go beyond managing blood sugar, said Dr