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The pharmacokinetics of LY3437943 (retatrutide) support once-weekly administration due to an elimination half-life of approximately 6 days. Jastreboff AM et al., Nature Medicine, 2023 This extended half-life is made possible by attaching a fatty acid chain to the peptide, allowing it to bind to albumin a common protein in your blood that acts like a slow-release carrier

As demand for new weight loss medications grows, there is increased focus on the insurance coverage landscape

In large studies, prescription treatments like Wegovy have helped people lose around 15% of their body weight over time