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Some preliminary research suggests berberine may indirectly increase endogenous GLP-1 secretion from intestinal cells, but this effect is fundamentally different from directly activating GLP-1 receptors
This prolongs incretin activity, increases postprandial insulin secretion from pancreatic beta cells, decreases glucagon secretion, delays gastric emptying, and lowers blood glucose levels (National Center for Biotechnology Information, 2023a)
The cross-stream pattern of complementary tissue-repair findings has produced the rationale researchers cite for combined-peptide investigations
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