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Developed by Novo Nordisk in the late 1990s, ipamorelin stimulates growth hormone (GH) release from somatotroph cells in the anterior pituitary gland through direct receptor activation, triggering the Gq/11-phospholipase C signalling cascade that leads to calcium-mediated exocytosis of GH-containing secretory granules

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Some patients affected with THMD4 may respond to high-dose thiamin supplementation (122)

Breakout Character: He was a minor character in Season 1 and vanished from the series afterwards, but his popularity eventually resulted in him being brought back roughly 16 years later as a prominent secondary character who's even gotten a few spotlight episodes