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In the early 1980s, Richard Goodman and P

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When GLP-1 receptors are activated, the pancreas releases more insulin in response to high blood glucose, suppresses glucagon (the hormone that raises blood sugar), and slows gastric emptying

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However, the semaglutide group received a relatively low dose, highlighting the need for further study

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Both companies are now positioning oral GLP-1s as a more accessible alternative to injections

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