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Immunofluorescence staining and western blot results verified that GPX1 expression was absent in the cochlear SGNs of gpx1 / mice (Supplementary Figures 1A,C), and there was no significant difference in SGNs number between the gpx1 / mice and WT mice (Supplementary Figure 1B), which indicated that the absence of GPX1 in normal SGNs would not affect the survival of SGNs
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The presence of this imbalance can significantly impact various physiological processes, resulting in a diverse array of health complications ( Endogenous antioxidant systems control ROS, chemically reactive molecules produced by cellular metabolism ( Oxidative stress caused by an imbalance in the adrenal hormones has many effects
