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Moving forward, the most realistic near-term translational path lies in combining relatively simple, biocompatible bone-targeted nanocarriers (such as alendronate-functionalized liposomal or polymeric systems) to specifically co-deliver immunogenic cell death (ICD)-inducing standard chemotherapeutics alongside established immune checkpoint inhibitors (e.g., anti-PD-1/PD-L1) or myeloid cell modulators
Omori H, Nishio M, Masuda M, Miyachi Y, Ueda F, Nakano T, et al
Tuning the geometry and optical chirality of pentatwinned Au nanoparticles with 5-fold rotational symmetry
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