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As the rate-limiting precursor of glutathione (GSH), cysteine can cause a decrease in the activity of GPX4 and a large accumulation of lipid peroxides when deficient, which eventually leads to ferroptosis
The importance and range of signaling pathways affecting appetite originating in the GIT, and thus the gut-brain axis, have been the subject of studies for a long time (Wessels, 2022)
PMC 3134129
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