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A widely cited study by Kraus and colleagues used genetic knockdown in mice

S1A), the cell ROS dichlorofluorescein (DCF) assay in combination with flow cytometry analysis demonstrated that WBC ROS accumulations during 1 h of 2 g/kg glucose challenge in the LOsG group were significantly higher than in the sham group (Fig

It remains under investigation in clinical trials registered on ClinicalTrials.gov and the EU Clinical Trials Register, and is not licensed for prescription or self-administration outside of formally approved research settings

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